背景與目的：慢性病自我管理課程（Chronic Disease Self-Management Program,CDSMP），以自我效能（self-efficacy theory）為基礎，設計自我管理13項工具之行動計畫以改善參與者之健康自我管理行為。本研究目的為運用CDSMP於思覺失調症患者，探究其健康狀況與日常活動功能之成效。方法：本研究招募80位受試者，以隨機分派方式分為實驗組及對照組，分別接受CDSMP六週課程或一般常規精神科治療，前、後測運用之成效評估工具為：美國史丹佛大學慢性病自我管理成效評估問卷（Stanford Self-Management Questionnaire, SSMQ）以及日常生活功能評量表第三版（Activities of Daily Living Rating Scale III, ADLRS-III）。結果：實驗組與對照組在SSMQ問卷項目之比較未達統計顯著（p = 0.131-0.988），SSMQ問卷的三個項目（呼吸短促情況、壓力情況和看診情況）顯示低度效應值（成功率差 [success rate difference] = 0.16-0.23），經二組在ADLRS-III之比較，呈現統計顯著（p = 0.008）及中度效應（Cohen’s d = 0.61）。結論：參與CDSMP課程可有效促進思覺失調症者之基本日常生活功能與工具性日常生活功能，可能有助於減輕壓力感受且增進就醫前的自我準備能力。整體而言，本研究顯示此課程在強化思覺失調症者自我照護方面可能具有潛在效益。

Background: The Chronic Disease Self-Management Program (CDSMP), grounded in selfefficacy theory, incorporates 13 self-management tools aimed at improving participants’ health behaviors through structured action planning. This study aimed to evaluate the effectiveness of the CDSMP on health outcomes and daily functioning in patients with schizophrenia. Methods: A total of 80 participants diagnosed with schizophrenia were randomly assigned to either an experimental group (receiving a six-week CDSMP course) or a control group (receiving routine psychiatric care). Outcomes were assessed using the Stanford Self-Management Questionnaire (SSMQ) and the Activities of Daily Living Rating Scale III (ADLRS-III), administered before and after the intervention. Results: The comparison between the experimental and control groups on the items of the SSMQ did not reach statistical significance (p = 0.131-0.988). For three items of the SSMQ (shortness of breath, stress, and visits your doctor), small effect sizes were observed (success rate difference = 0.16-0.23). A statistical significance was found in the ADLRS-III between two groups (p = 0.008) with moderate effect size (Cohen’s d = 0.61). Conclusion: Participation in the CDMSP may effectively basic and instrumental activities of daily living in patients with schizophrenia. The CDSMP may have help alleviate perceived stress and to enhance preparedness before medical visits. Overall, this study suggests that the program may have potential benefits in strengthening self-care in patients with schizophrenia.